Hard capsule manufacturing models and classifications

Hard capsule manufacturing is when dietary supplement manufacturers make a certain amount of edible raw and auxiliary materials into uniform powders or granules and fill them into hollow capsules in the GMP workshop, or directly pack the raw and auxiliary powders into hollow capsules. Commodity processing services. Moreover, there are many categories of capsule models and materials.

Model of capsule shell for hard capsule manufacturing

There are eight specifications of hard capsules, and the commonly used sizes are 0-5. 0# has a capacity of 0.75ml, 1# has a capacity of 0.55ml, 2# has a capacity of 0.40ml, 3# has a capacity of 0.30ml, 4# has a capacity of 0.25ml, and 5# has a capacity of 0.15ml. Safety capsules among hard capsules are hard capsules that are difficult to open without damage after the capsule body cap is locked. The models are divided into 5 specifications: A, B, C, D, and E. Its volume is equivalent to standard capsule sizes 0, 1, 2, 3, and 4.

What are the types of hard capsule manufacturing?

1. Gelatin hard capsule manufacturing: using gelatin as the main raw material, capsule shells with specific colors and shapes. It does not require adhesives and high pressure during the production process, and is easy to disintegrate and release in gastric juice. Compared with tablets and pills, it can improve bioavailability. At the same time, it has the advantages of accurate dosage, easy to carry and use, and safe sealing. It dissolves in water at 30°C. It absorbs water, expands and deforms at low temperatures. The water content at the factory is between 13% and 16%. At relative humidity of 35% ~ 65% and temperature of 15 ~ 25℃, the product can be kept for 24 months. Ideal storage conditions: relative humidity 50%, temperature 21°C.

2. Enteric gelatin hard capsule manufacturing: It is a capsule shell with a specific color and shape made of gelatin and enteric coating materials. It does not disintegrate without cracks in gastric juice for two hours, and disintegrates and dissolves in intestinal juice within 30 minutes. , providing complete solutions for proteins, peptides and live bacterial preparations.

3. Colon dissolving hard capsule manufacturing: It is a capsule product carefully prepared through scientific formula and special coating materials using medicinal gelatin. The product remains in the gastric juice for two hours and in the intestinal juice for three hours without cracks or disintegration. It disintegrates and releases at a specific point in the colon within 30 minutes. Its appearance and quality are equivalent to those of hollow capsules.

4. Plant hard capsule manufacturing: Made from plant cellulose raw materials, in addition to the advantages of natural concept, plant capsules can also enhance the absorption and digestion of protein, fat and carbohydrates, and have technical advantages and characteristics that traditional gelatin capsules do not have. . The color of plant capsule shells is mostly transparent, and most of them are lighter in color. It is the best choice for domestic and foreign customers to make high-end products.

Hard capsules account for a large proportion of the dosage forms of dietary supplement manufacturers, second only to tablets. Export trade orders in the field of nutritional supplement contract manufacturing are particularly prominent. The preparation has a neat appearance, uniform ingredient content, no odor, and has obvious advantages of being easy to carry and store.