GMP certified effervescent supplement manufacturing

Because the production and manufacturing of effervescent tablet supplements is restricted by the production environment, it cannot be done by non-capable GMP certified factories. This also provides screening conditions for customers seeking OEM cooperation in the production of professional tablet manufacturers. Many customers who are engaged in OEM production of effervescent tablets for the first time are somewhat unclear about the reasons. Below, the editor will share with you the relevant knowledge about the commissioned production of effervescent tablets and supplements.

Instructions for manufacturing effervescent supplements

Effervescent tablets are tablets containing effervescent disintegrants. The principle of effervescence is to use organic acids and basic carbonate (hydrogen) salts to react to produce a large amount of carbon dioxide gas, which is like boiling. Therefore, the product is extremely absorbent and will change in a short time when exposed to water. Therefore, there are strict requirements for the production process, workshop environment, and packaging materials. details as follows:

1. Production process of effervescent supplements: During the production process, mixed raw materials and semi-finished bare chips are exposed to the air, so the time of this process needs to be shortened as much as possible. This requires health care product manufacturers with professional tablet processing and production capabilities to make sufficient preparations for the connection of production equipment and the flow of each process to avoid affecting product quality during the production process.

2. GMP certified workshop: This condition basically limits the possibility of small manufacturers to produce effervescent supplements. The temperature, humidity, air pressure, and amount of dust in the workshop production environment can all affect product quality, especially the control of temperature and humidity. Because effervescent tablet products have extremely strict requirements on air humidity, even powerful GMP factories located in the north may not be able to produce them around the clock.

3. Special packaging materials for effervescent tablet supplements: Although effervescent tablets are a type of tablet product, because they have strong moisture absorption, ordinary aluminum foil bags, PET bottles, and blister caps cannot meet their transportation and storage conditions. For example, desiccants. Ordinary tablet desiccants have a higher water content than effervescent tablets, and their water absorption is not as good as effervescent tablet products. They cannot function as desiccants at all, so special desiccants are not required. Most effervescent tablet packaging bottles are long cylindrical bottles, which can effectively reduce the collision of large tablets and have a strong sealing effect.

Six major systems of GMP certified factory certified workshops

1. Quality system

2. Laboratory system

3. Production system

4. Facilities and equipment systems

5. Material system

6. Packaging and labeling system

GMP is a set of mandatory standards applicable to pharmaceutical, food and other industries. It requires enterprises to meet health quality requirements in accordance with relevant national regulations in terms of raw materials, personnel, facilities and equipment, production processes, packaging and transportation, quality control, etc., and form an operational set of standards. The operating specifications help companies improve their hygienic environment and promptly identify problems in the production process and improve them.

Advantages of effervescent supplement manufacturers

1. The OEM factory provides customized services for special packaging materials for effervescent tablets;

2. The processing factory provides customers who do not have formula research and development capabilities with a full set of research and development services from dosage form, taste, effervescent effect and functional formula;

3. The factory has GMP workshop certification, SC, ISO22000 and other complete qualifications, and can provide all-round product quality assurance.

Pesicon Holdings is a source manufacturer that can provide tablet OEM production services such as chewable tablet processing, decoction tablet customization, buccal tablet OEM and effervescent tablet OEM processing. It is a powerful factory in China with FDA registration and cGMP certification.