12 Proven Benefits and Side Effects of Vitamin B12

Vitamin B12 (Vitamin B12), also known as cobalamin (cobalamin) or vitamin B12, is the most special type of vitamin B group (containing metal ion cobalt), with a large and complex structure.

In addition to pernicious anemia, a deficiency of this nutrient can cause symptoms such as homocysteinemia (associated with cardiovascular disease), peripheral neuropathy, cognitive impairment, loss of appetite, and burnout.

Deficiency can occur even with normal vitamin B12 levels

A case report noted that up to 50% of patients with clinically symptomatic vitamin B12 deficiency may have "normal" levels of vitamin B12 (over 200 pg/mL).

Therefore, in patients with normal B12 levels but suspected vitamin B12 deficiency, especially when levels are borderline normal, clinicians should measure methylmalonic acid and homocysteine levels to confirm treatment direction.

1. Vitamin B12 May Help Diabetic Neuropathy

2. Vitamin B12 Benefits Autism Spectrum Disorders

3. Treatment of vitamin B12 selective malabsorption syndrome

4. Vitamin B12 for cyanide poisoning (caused by inhalation of fire smoke)

5. Vitamin B12 may benefit gestational diabetes

6. Vitamin B12 is beneficial for cardiovascular and cerebrovascular diseases

7. Vitamin B12 improves herpetic neuralgia

8. Vitamin B12 reduces risk of colorectal cancer

9. Vitamin B12 may benefit osteoporosis

10. Vitamin B12 Reduces Neural Tube Defects

11. Vitamin B12 is beneficial for depression

12. Vitamin B12 reduces risk of premature birth

Are there any side effects of vitamin B12?

Vitamin B12 is considered to be non-toxic and has no side effects for generally healthy people and when used in appropriate dosages.

Although the "Upper Tolerable Intake Level" (Upper Tolerable Intake Level) of vitamin B12 has not been established, there is a risk of excessive B12 intake in large doses.

Possible side effects or adverse reactions when taking large doses of vitamin B12 include: dizziness, headache, anxiety, nausea, vomiting, itching, acne (acne) and rosacea (rosacea).

In addition, there have been cases of severe allergic reactions caused by vitamin B12. Although it is extremely rare, it must still be noted. Symptoms include swelling of the face, tongue and throat, and difficulty swallowing and breathing. If these conditions occur after taking it, please seek medical help immediately.